ABC transporters TetB and TetA fromCorynebacterium striatum plasmid pTP10
ID CX21300 standard; DNA; PRO; 8990 BP.
XX
AC U21300;
XX
NI g4019167
XX
DT 29-MAR-1995 (Rel. 43, Created)
DT 17-DEC-1998 (Rel. 58, Last updated, Version 4)
XX
DE Corynebacterium striatum plasmid pTP10 hypothetical protein YbhB
DE gene, partial cds; ABC transporter TetB (tetB), ABC transporter
DE TetA (tetA), transposase, erythromycin methyltransferase (ermCX),
DE and transposase genes, complete cds; and unknown genes.
XX
KW .
XX
OS Corynebacterium striatum
OC Bacteria; Firmicutes; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Corynebacterineae; Corynebacteriaceae; Corynebacterium.
XX
OS Corynebacterium xerosis
OC Bacteria; Firmicutes; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Corynebacterineae; Corynebacteriaceae; Corynebacterium.
XX
OG Plasmid pTP10
XX
RN [1]
RP 1-8990
RX MEDLINE; 96117603.
RA Tauch A., Kassing F., Kalinowski J., Puhler A.;
RT "The Corynebacterium xerosis composite transposon Tn5432 consists of two
RT identical insertion sequences, designated IS1249, flanking the
RT erythromycin resistance gene ermCX";
RL Plasmid 34(2):119-131(1995).
XX
RN [2]
RP 1-8990
RA Tauch A., Krieft S., Kalinowski J., Puehler A.;
RT "The tetAB genes of the Corynebacterium striatum R-plasmid pTP10 encode
RT an ABC transporter and confer tetracycline, oxytetracycline, and
RT oxacillin resistance in Corynebacterium glutamicum";
RL Unpublished.
XX
RN [3]
RP 1-8990
RA Kalinowski J.;
RT ;
RL Submitted (20-FEB-1995) to the EMBL/GenBank/DDBJ databases.
RL Joern Kalinowski, University of Bielefeld, Department of Genetics,
RL Bielefeld, 33501, Germany
XX
RN [4]
RP 1-8990
RA Tauch A., Krieft S., Kalinowski J., Puehler A.;
RT ;
RL Submitted (15-DEC-1998) to the EMBL/GenBank/DDBJ databases.
RL Joern Kalinowski, University of Bielefeld, Department of Genetics,
RL Bielefeld, 33501, Germany
XX
DR SPTREMBL; Q46483; Q46483.
DR SPTREMBL; Q46484; Q46484.
DR SPTREMBL; Q46485; Q46485.
DR SPTREMBL; Q46486; Q46486.
DR SPTREMBL; Q57090; Q57090.
XX
CC On Dec 15, 1998 this sequence version replaced gi:709804.
XX
FH Key Location/Qualifiers
FH
FT source 1..8990
FT /organism="Corynebacterium striatum"
FT /strain="M82B"
FT /plasmid="pTP10"
FT CDS complement(<1..102)
FT /codon_start=1
FT /db_xref="PID:g4019170"
FT /note="orf8"
FT /transl_table=11
FT /product="hypothetical protein YbhB"
FT /translation="MTANYVSDRFPGPDPYAALADVPSFDITSEDIVD"
FT CDS complement(124..1710)
FT /codon_start=1
FT /db_xref="PID:g4019169"
FT /transl_table=11
FT /gene="tetB"
FT /product="ABC transporter TetB"
FT /translation="MAPDYARTDAVAPASVKETFAYLSALPNALDRRWWAGLLLIQALI
FT VAVYTTQSNLFGRSVDPLTGGEVPLLGTGTRAFVWTVGLALACMLVEMFLRALGNYVVG
FT LKVARASIDLRRRCLDAILRAPVPRVMELGTGNVITRMTKDIDDVVQTITAIGSRVLTT
FT VFVFPITFIGLLLIDVRFALILLLICICTYPFARAVVRAIPDASNAVSVAEARRNAVLL
FT DTVRGLPTLRAFDLERWALARMRRTSWGAVEAEMDRVHWFIRLTGIGQVAFAAWVLLTL
FT GVGAWLASAGVVTRAAQRAGRPLCHARGGTTTALVGTSGAGKSTLAALIAGLVEPTAGS
FT IRVGAVETSQVSDTWTAKNVTLLTQDVHLFAGTLREDLSMAAQDATDADLLRALASVGL
FT DPEGTQFARLFPKGLDTAVGAGAEDIPPEVEQQLALARVALSGPKVLILDEATAEAGSD
FT ATNALEDAAARITADTTALVVAHRLDQAAAADRILVMDAGRIIEDGTHTELVAADGRYA
FT QLFAAWSGGGH"
FT CDS complement(1711..3252)
FT /codon_start=1
FT /db_xref="PID:g4019168"
FT /transl_table=11
FT /gene="tetA"
FT /product="ABC transporter TetA"
FT /translation="MKTYSWFVPPAPPADDPARLHPARWSSGNRVVRDMVGAYPGVLVL
FT HILSYLIGSGISAFVPVVVGMIVDGLVGEEKFNAWWLFAVLVGIFIIQFIGEATGDGLA
FT TASVRRVTHNAQQHLSSGVLRRGAGAMSPGTVLNTIDADANTVGRYRELLSFPLMAIGY
FT AVCAMVAMWSVSPWISLAIPASALIIALFAAWTAGPVTRVSLKRRAAEADVAGLATDAS
FT QGIRTVKGLGAGATVATRFHAETAKANGLMLTHLRVEVWLGFARFCVAWLCNLGIVGLS
FT AWMTLRGEITPGQLTSVALLVQPALTMAGLAFGDLASGWGRAVASGQRIEQLHHAGDDA
FT AGPEPTDTPVPGAGLWILEPAERSYATAAAWAQRADVLFPPHTVNVFEGTIADNVNPRG
FT DVPEDVVKQALAAAHCQDILRRLGGINEAGELPDAPLGEAGLNLSGGQRQRVALARALA
FT ADPEVLILDDPTTGLDSVTQADVVAAVAALRADKTTVVITGNAAWQHAGTELEVA"
FT repeat_unit complement(3294..3338)
FT /label=IR1
FT /note="inverted"
FT source 3294..4678
FT /organism="Corynebacterium striatum"
FT /insertion_seq="IS1249"
FT /strain="M82B"
FT source 3294..7817
FT /organism="Corynebacterium striatum"
FT /note="composite transposon"
FT /transposon="Tn5432"
FT /strain="M82B"
FT CDS 3425..4633
FT /codon_start=1
FT /db_xref="PID:g709805"
FT /db_xref="SPTREMBL:Q57090"
FT /label=ORF1
FT /transl_table=11
FT /product="transposase"
FT /translation="MLCAAWCGVAMSKNQPRCHCGGEMKRNGTTSKGTTRWRCKQCGAS
FT SVKRRNDITNAAVFTQFIEHCTTAISLDDLAKRNGVSRATMKRRFKWCWLVDVPDPTAG
FT HHKRIYDQVFLDGTYTAGGCLIVAATIDHVIAWHWCKHETTRDYQLLLERIEAPLIAVI
FT DGGQGAYSAIKKCWPTTKIQRCLVHAQRVVRRYTTTNPRTDAGRTIYRLALKLTRITTL
FT DEAAAWGVQLHEFSTIYREWMNEKTMIKDPKTGAWTRVWTHHNVRKAYNSLNHLWRSEM
FT LFVYLNPPAGVLAPERIKSTTNSLEGGINAQLKLLARTHRGRSGERQRRMLDWWLYLKT
FT ELPDDPVRIARQSDWGQGQLAKVSTLTQTENQADHETGRPALYDNAIDTDYTHSIGIQK
FT GQI"
FT repeat_unit 4637..4678
FT /rpt_family="IR2"
FT /rpt_type=INVERTED
FT -35_signal 4665..4670
FT misc_feature 4679..6356
FT /note="similar to the erythromycin resistance region of the
FT Corynebacterium diphtheriae plasmid pNG2, GenBank Accession
FT Number X51472"
FT -10_signal 4689..4694
FT CDS 4849..5610
FT /codon_start=1
FT /db_xref="PID:g709806"
FT /db_xref="SPTREMBL:Q46484"
FT /label=ORF2
FT /transl_table=11
FT /gene="ermCX"
FT /product="erythromycin methyltransferase"
FT /translation="MSAYGHGRHEHGQNFLTNHKIINSIIDLVKQTSGPIIEIGPGSGA
FT LTHPMAHLGRAITAVEVDAKLAAKITQETSSAAVEVVHDDFLNFRLPATPCVIVGNIPF
FT HLTTAILRKLLHAPAWTDAVLLMQWEVARRRAGVGASTMMTAQWSPWFTFHLGSRVPRP
FT AFRPQPNVDGGILVIRRVGDPKIPIEQRKAFQAMVHTVFTARGRGIGEILRRQGCFHHV
FT QKHNHGCAREESTPRPYLPDCTPTTGSISSR"
FT CDS 5867..6439
FT /codon_start=1
FT /db_xref="PID:g709807"
FT /db_xref="SPTREMBL:Q46485"
FT /label=ORF3
FT /note="possible transposase fragment; similar to the
FT transposase protein of IS31831 from Corynebacterium
FT glutamicum ssp. flavum, PIR Accession Number S43613, and
FT Mycobacterium smegmatis IS1096 tnpA gene product, encoded
FT by GenBank Accession Number M76495"
FT /transl_table=11
FT /product="unknown"
FT /translation="MQPNGNVIVDTICRTAKLGTTITGATENGDVTVIEAEPVEPINEC
FT PTCGQPGVFRDHVIRSLVDLPIVGHPTTSCAPSTLPVHQQALLAEDLPCWPCLRARQFK
FT DHGPGDPLDPATTLPKSDERCRCTQVIRPGVGYEVSQVLFRLMKPVFETTYGAQRTPMP
FT KLPQHRLPHQTHDSGIHTLNPHACNLG"
FT repeat_unit complement(6433..6477)
FT /rpt_family="IR3"
FT /rpt_type=INVERTED
FT source 6433..7817
FT /organism="Corynebacterium xerosis"
FT /insertion_seq="IS1249"
FT /strain="M82B"
FT CDS 6564..7772
FT /codon_start=1
FT /db_xref="PID:g709808"
FT /db_xref="SPTREMBL:Q57090"
FT /label=ORF4
FT /transl_table=11
FT /product="transposase"
FT /translation="MLCAAWCGVAMSKNQPRCHCGGEMKRNGTTSKGTTRWRCKQCGAS
FT SVKRRNDITNAAVFTQFIEHCTTAISLDDLAKRNGVSRATMKRRFKWCWLVDVPDPTAG
FT HHKRIYDQVFLDGTYTAGGCLIVAATIDHVIAWHWCKHETTRDYQLLLERIEAPLIAVI
FT DGGQGAYSAIKKCWPTTKIQRCLVHAQRVVRRYTTTNPRTDAGRTIYRLALKLTRITTL
FT DEAAAWGVQLHEFSTIYREWMNEKTMIKDPKTGAWTRVWTHHNVRKAYNSLNHLWRSEM
FT LFVYLNPPAGVLAPERIKSTTNSLEGGINAQLKLLARTHRGRSGERQRRMLDWWLYLKT
FT ELPDDPVRIARQSDWGQGQLAKVSTLTQTENQADHETGRPALYDNAIDTDYTHSIGIQK
FT GQI"
FT repeat_unit 7776..7817
FT /rpt_family="IR4"
FT /rpt_type=INVERTED
FT CDS 8117..8743
FT /codon_start=1
FT /db_xref="PID:g709809"
FT /db_xref="SPTREMBL:Q46486"
FT /label=ORF5
FT /note="possible rep or par function; similar to the RepB
FT protein of Enterococcus faecalis plasmid pAD1, PIR
FT Accession Number B47092, and the ParA protein of
FT Agrobacterium tumefaciens plasmid pTAR, Swiss-Prot
FT Accession Number P05682"
FT /transl_table=11
FT /product="unknown"
FT /translation="MPVISCLNAKGGTGKTTSAINLAAVAAYRGYTVHVLDADAEQGTA
FT SEWIEYANDAFEENPNAPHVDVEVEAVNRGILARKVKKYSDDLVIIDGPPSNHSMSELI
FT IENSDFVVIPTTGTHTDMAQTWKIIDVIPEGKHYAVLPTIWDKRKSTADRARKVLEDEG
FT IPVIWPGVESRAYFDRQFGHWPRNSAKELHGYPAIFDKIIAQITN"
XX
SQ Sequence 8990 BP; 2062 A; 2998 C; 2446 G; 1484 T; 0 other;
GTCGACGATG TCCTCGGACG TGATGTCGAA GGACGGCACG TCCGCCAGCG CGGCGTACGG 60
GTCGGGGCCG GGGAAACGGT CGGAAACATA ATTTGCAGTC ATGTCCCCAT TCCTACCGGA 120
GAGTTAGTGA CCGCCGCCAC TCCACGCAGC GAACAGTTGC GCGTATCTCC CGTCGGCGGC 180
GACGAGTTCG GTGTGGGTGC CGTCCTCGAT GATGCGCCCG GCGTCCATGA CCAGGATCCG 240
GTCCGCGGCC GCCGCCTGGT CTAGGCGGTG CGCCACCACC AGTGCCGTGG TGTCTGCGGT 300
GATCCGCGCG GCGGCGTCCT CCAGCGCGTT CGTGGCGTCG CTGCCGGCTT CCGCTGTGGC 360
CTCGTCCAGG ATGAGCACCT TCGGGCCCGA CAGCGCCACG CGTGCGAGCG CGAGCTGCTG 420
CTCCACCTCC GGGGGTATGT CCTCCGCGCC TGCGCCGACG GCGGTGTCCA GCCCCTTCGG 480
GAACAGGCGC GCGAACTGGG TGCCTTCAGG GTCGAGCCCG ACACTTGCCA GCGCCCGCAG 540
CAGGTCCGCG TCGGTCGCAT CCTGTGCGGC CATCGAGAGG TCCTCGCGCA GGGTGCCGGC 600
GAACAGGTGG ACGTCCTGGG TGAGCAGGGT GACGTTCTTG GCGGTCCACG TGTCGCTGAC 660
CTGCGAGGTT TCCACGGCCC CTACCCGGAT GCTCCCAGCT GTGGGCTCCA CCAGCCCCGC 720
AATGAGCGCG GCGAGCGTGG ACTTGCCGGC GCCCGAAGTG CCCACCAGCG CGGTGGTTGT 780
TCCGCCTCGA GCGTGACAGA GAGGTCTTCC AGCACGTTGC GCCGCCCGGG TGACAACTCC 840
GGCCGACGCG AGCCACGCGC CGACGCCAAG CGTGAGCAGC ACCCACGCGG CGAAAGCGAC 900
CTGGCCGATG CCTGTGAGCC GGATGAACCA GTGCACACGG TCCATCTCCG CCTCCACCGC 960
GCCCCACGAG GTCCGCCGCA TCCGTGCCAA CGCCCAGCGC TCCAAGTCGA AGGCGCGCAG 1020
CGTGGGCAGG CCCCGGACGG TATCCAGCAG CACCGCGTTG CGACGCGCCT CCGCCACGCT 1080
CACCGCGTTG GAGGCATCCG GGATGGCGCG GACCACCGCG CGGGCGAACG GGTACGTGCA 1140
GATGCAGATC AAAAGCAGGA TCAAGGCGAA GCGGACGTCG ATAAGCAAAA GCCCGATAAA 1200
CGTGATCGGA AAGACGAACA CGGTGGTGAG CACGCGCGAG CCGATGGCGG TGATGGTTTG 1260
GACGACGTCG TCGATGTCCT TGGTCATGCG TGTGATCACG TTGCCGGTGC CGAGCTCCAT 1320
CACCCGCGGC ACAGGTGCGC GCAGGATCGC GTCGAGGCAG CGACGGCGCA AGTCGATGGA 1380
CGCGCGGGCG ACCTTGAGGC CCACCACGTA GTTACCGAGG GCGCGCAGGA ACATCTCGAC 1440
GAGCATGCAG GCCAACGCCA GTCCAACAGT CCACACAAAG GCGCGGGTGC CGGTGCCCAG 1500
TAGCGGCACC TCGCCTCCGG TGAGCGGGTC GACGCTGCGC CCGAACAGGT TCGACTGCGT 1560
GGTGTACACG GCGACGATGA GCGCCTGGAT GAGCAGCAGA CCCGCCCACC AGCGTCTGTC 1620
CAGCGCGTTG GGCAGCGCCG AGAGGTACGC GAAGGTCTCC TTCACACTTG CGGGTGCGAC 1680
CGCGTCTGTG CGTGCGTAAT CGGGCGCCAT CTACGCCACC TCCAATTCGG TTCCAGCGTG 1740
CTGCCACGCG GCGTTTCCGG TGATGACCAC GGTGGTTTTG TCTGCTCTGA GCGCGGCGAC 1800
GGCTGCCACG ACGTCCGCCT GTGTCACGGA ATCGAGCCCC GTGGTCGGGT CGTCCAGGAT 1860
GAGCACCTCC GGGTCGGCGG CGAGCGCCCT GGCAAGCGCG ACGCGCTGGC GCTGCCCGCC 1920
GGAAAGGTTC AGGCCGGCCT CCCCCAGCGG CGCGTCCGGC AACTCGCCTG CTTCGTTGAT 1980
ACCGCCGAGC CTGCGGAGGA TGTCTTGGCA GTGGGCGGCG GCGAGCGCCT GCTTGACGAC 2040
GTCCTCCGGC ACATCCCCGC GCGGGTTCAC GTTGTCTGCG ATGGTGCCCT CAAACACGTT 2100
GACGGTGTGC GGCGGGAACA GCACGTCTGC GCGCTGCGCC CACGCGGCGG CGGTGGCGTA 2160
GGAACGCTCC GCCGGCTCGA GAATCCACAG CCCCGCGCCT GGGACCGGGG TGTCTGTCGG 2220
CTCAGGCCCC GCCGCGTCAT CGCCCGCGTG GTGCAGCTGC TCGATGCGCT GGCCACTCGC 2280
GACGGCCCTG CCCCACCCGC TGGCCAGGTC GCCGAACGCT AAGCCCGCCA TGGTCAACGC 2340
AGGCTGCACC AACAGTGCCA CGGATGTCAG CTGCCCCGGG GTGATCTCCC CGCGCAGCGT 2400
CATCCACGCG CTCAAGCCCA CGATGCCAAG GTTGCACAGC CACGCCACGC AAAACCTGGC 2460
GAAACCGAGC CACACCTCCA CACGCAGGTG CGTGAGCATC AAGCCGTTCG CCTTCGCCGT 2520
TTCGGCGTGA AAACGTGTTG CCACGGTTGC ACCCGCGCCT AGGCCTTTGA CGGTGCGAAT 2580
GCCTTGCGAC GCATCCGTGG CCAAGCCAGC GACATCCGCC TCCGCGGCGC GACGCTTCAA 2640
CGACACCCGC GTCACCGGCC CCGCGGTCCA CGCGGCGAAC AGAGCGATGA TCAGCGCGCT 2700
GGCCGGGATG GCCAGTGAGA TCCACGGGGA GACCGACCAC ATCGCCACCA TCGCGCAGAC 2760
CGCGTAGCCG ATGGCCATGA GCGGAAACGA CAGCAGCTCG CGGTAGCGGC CGACGGTGTT 2820
CGCGTCCGCG TCGATGGTGT TGAGTACGGT GCCGGGGCTC ATCGCTCCCG CCCCGCGGCG 2880
CAGCACGCCC GAGGACAGGT GCTGCTGCGC GTTGTGGGTC ACGCGGCGCA CCGAGGCTGT 2940
GGCCAGGCCG TCGCCGGTGG CCTCGCCGAT GAACTGGATG ATGAAGATGC CGACCAATAC 3000
TGCGAAGAGC CACCATGCGT TGAACTTTTC TTCCCCCACC AGGCCGTCCA CGATCATGCC 3060
CACCACCACC GGCACAAACG CGGAGATGCC GGAGCCGATG AGGTAGCTCA GAATGTGCAG 3120
CACTAGCACG CCCGGGTATG CGCCTACCAT GTCCCTGACC ACACGGTTCC CGCTGCTCCA 3180
GCGTGCTGGG TGGAGCCGCG CCGGATCGTC CGCTGGCGGC GCGGGCGGGA CGAACCAGCT 3240
GTACGTCTTC ATTCTGCGCG GCGGTGGCAT CATTCTGGAA AATCTAGCAT ATTGGGTTAA 3300
GGGTCAAAAA GTGTGTCCGG AATCGCGGAT TTTCACGGAT TGACCTGTAG GTTTCCGGAA 3360
AGTATATGCT CCGGAAGCAT ATATCTAGCC CCCGACGGGA AATCCTCGGT GTGGCAGCCG 3420
TGATGTGCTA TGCGCGGCGT GGTGTGGTGT CGCAATGTCG AAGAACCAAC CACGCTGCCA 3480
CTGCGGCGGT GAAATGAAAC GCAACGGCAC CACCAGCAAA GGCACCACCA GATGGCGCTG 3540
CAAACAATGC GGCGCCTCCA GCGTCAAACG TCGAAACGAC ATCACCAACG CGGCAGTGTT 3600
CACCCAGTTC ATCGAGCATT GCACCACCGC AATATCACTC GACGACCTAG CCAAACGAAA 3660
CGGTGTTAGC CGCGCCACCA TGAAGCGGCG CTTCAAGTGG TGCTGGCTCG TTGATGTGCC 3720
TGACCCCACC GCCGGCCACC ACAAGCGGAT CTACGACCAG GTATTTCTCG ATGGCACCTA 3780
CACCGCCGGT GGCTGCCTGA TCGTCGCGGC GACCATCGAC CACGTGATCG CCTGGCACTG 3840
GTGCAAACAC GAAACCACCC GCGACTACCA ACTGCTGCTT GAACGCATCG AAGCCCCACT 3900
CATCGCCGTC ATCGACGGCG GCCAAGGCGC ATACAGCGCA ATCAAAAAGT GCTGGCCGAC 3960
TACGAAAATT CAACGCTGCC TCGTCCACGC CCAACGCGTG GTCCGCCGCT ACACCACCAC 4020
CAACCCACGC ACCGATGCCG GGCGCACCAT CTACCGACTT GCGCTGAAAC TGACCCGGAT 4080
CACCACACTG GATGAAGCCG CCGCGTGGGG TGTGCAACTG CACGAGTTTT CAACGATCTA 4140
CCGGGAATGG ATGAACGAGA AAACCATGAT CAAAGACCCC AAAACAGGTG CATGGACCCG 4200
CGTGTGGACC CACCACAACG TGCGCAAGGC CTACAACAGC CTCAACCATC TTTGGCGGTC 4260
CGAGATGCTG TTTGTCTACC TCAACCCGCC AGCAGGAGTC CTTGCGCCCG AGCGGATCAA 4320
ATCCACCACC AACAGCTTAG AAGGCGGCAT CAACGCCCAG CTCAAACTGC TCGCCAGAAC 4380
CCACCGCGGC AGATCAGGCG AACGACAACG CCGCATGCTG GATTGGTGGC TCTACTTAAA 4440
AACGGAACTG CCTGACGATC CAGTACGAAT CGCCAGGCAG TCCGACTGGG GCCAGGGCCA 4500
ACTCGCCAAA GTATCCACCC TGACCCAAAC CGAGAACCAA GCCGACCACG AAACAGGACG 4560
CCCAGCCCTC TACGACAACG CTATCGACAC CGACTACACC CACTCAATCG GCATTCAAAA 4620
AGGCCAAATC TAACCCCCGC GACACGCCGA GCCAGACACA CATTTTGACC CTTAACCCTT 4680
TAAATGGATA TAATTAGACC CATGTTGATT TCAGGTACCG CTTTCTTGCG GTTGCGCACC 4740
AACCGCTAAG GCGGTTTCCT ACCCCGTAGG TTAAAAACCG CTCCGGTCCT TTAGCCGGGC 4800
GGCTATTTGT CATGCCCGGC TCCCTTTCAA ATCCAAGGAG CACACCTGAT GTCTGCATAC 4860
GGACACGGCC GTCACGAGCA TGGCCAAAAT TTTCTCACCA ACCACAAGAT CATCAACTCC 4920
ATCATCGACC TTGTGAAACA AACCTCCGGC CCCATCATTG AGATCGGACC AGGAAGCGGT 4980
GCCCTCACTC ACCCGATGGC CCACTTGGGG AGGGCGATAA CGGCAGTTGA AGTGGACGCA 5040
AAACTAGCTG CCAAAATCAC ACAAGAAACC TCCTCGGCGG CGGTCGAAGT GGTCCATGAT 5100
GATTTCCTTA ACTTCCGGTT ACCCGCCACT CCCTGCGTCA TTGTGGGAAA CATTCCCTTT 5160
CACCTCACCA CTGCCATTCT TCGAAAGTTG CTGCATGCGC CAGCATGGAC TGACGCTGTA 5220
CTCCTCATGC AGTGGGAAGT CGCTCGCCGC CGGGCCGGGG TAGGCGCAAG CACGATGATG 5280
ACGGCTCAGT GGTCCCCATG GTTCACATTT CACCTGGGTT CTCGGGTACC AAGGCCTGCT 5340
TTCCGGCCAC AGCCAAACGT TGACGGGGGG ATCTTAGTGA TCCGCCGGGT GGGTGACCCG 5400
AAGATTCCGA TAGAGCAGCG CAAAGCCTTT CAGGCGATGG TGCACACCGT TTTCACTGCC 5460
CGGGGACGCG GGATAGGGGA AATTCTCCGA AGGCAGGGTT GTTTTCATCA CGTTCAGAAA 5520
CACAATCATG GTTGCGCTCG CGAGGAATCG ACCCCGCGAC CCTACCTCCC AGATTGCACA 5580
CCAACGACTG GATCGATCTC TTCCAGGTGA CTGGTTCCTC TCTACCTCAC CATCGACCCA 5640
TTTCACCATC GGGAAGTAGT CAACGACCTC CTCAACGGAA AAACCGAAGC CGGCGGCGTT 5700
AATCCCCACC AAAACCGAAA TCCACCAGTA GTACTAAAAG GGCTCTTCCG GTTTTAGAGT 5760
GCATTGATTA GTTCGCCGGG GGTTCGGGCG TGGCACAAGA TATTGGGGTC CTTGGCTTTG 5820
TAGGAAAAAG GTATCTAATC CATCCGTACA AAACTAAGGA CCTACTGTGC AGCCTAACGG 5880
AAATGTCATC GTCGATACCA TCTGCCGCAC CGCAAAACTA GGAACTACTA TCACCGGTGC 5940
CACAGAAAAC GGTGACGTCA CTGTTATTGA AGCCGAACCC GTCGAGCCGA TCAATGAATG 6000
CCCTACCTGC GGGCAGCCTG GAGTATTCCG CGACCACGTC ATCCGCAGCC TGGTCGATCT 6060
GCCCATCGTC GGCCACCCAA CAACTTCATG TGCGCCTTCC ACGCTACCGG TGCACCAACA 6120
AGCGTTGCTT GCAGAAGATC TTCCGTGCTG GCCTTGCCTG CGCGCCCGAC AATTCAAAGA 6180
CCACGGACCA GGTGACCCAC TGGATCCTGC AACGACTCTG CCTAAATCGG ATGAGCGTTG 6240
CCGCTGCACC CAAGTCATTA GGCCTGGGGT GGGATATGAA GTGTCCCAGG TTTTGTTCCG 6300
TTTGATGAAA CCCGTTTTTG AAACAACGTA CGGAGCACAA CGCACGCCGA TGCCAAAGCT 6360
TCCGCAACAT CGACTACCTC ATCAAACCCA CGACAGTGGG ATTCACACCC TCAATCCCCA 6420
CGCGTGCAAT CTGGGTTAAG GGTCAAAAAG TGTGTCCGGA ATCGCGGATT TTCACGGATT 6480
GACCTGTAGG TTTCCGGAAA GTATATGCTC CGGAAGCATA TATCTAGCCC CCGACGGGAA 6540
ATCCTCGGTG TGGCAGCCGT GATGTGCTAT GCGCGGCGTG GTGTGGTGTC GCAATGTCGA 6600
AGAACCAACC ACGCTGCCAC TGCGGCGGTG AAATGAAACG CAACGGCACC ACCAGCAAAG 6660
GCACCACCAG ATGGCGCTGC AAACAATGCG GCGCCTCCAG CGTCAAACGT CGAAACGACA 6720
TCACCAACGC GGCAGTGTTC ACCCAGTTCA TCGAGCATTG CACCACCGCA ATATCACTCG 6780
ACGACCTAGC CAAACGAAAC GGTGTTAGCC GCGCCACCAT GAAGCGGCGC TTCAAGTGGT 6840
GCTGGCTCGT TGATGTGCCT GACCCCACCG CCGGCCACCA CAAGCGGATC TACGACCAGG 6900
TATTTCTCGA TGGCACCTAC ACCGCCGGTG GCTGCCTGAT CGTCGCGGCG ACCATCGACC 6960
ACGTGATCGC CTGGCACTGG TGCAAACACG AAACCACCCG CGACTACCAA CTGCTGCTTG 7020
AACGCATCGA AGCCCCACTC ATCGCCGTCA TCGACGGCGG CCAAGGCGCA TACAGCGCAA 7080
TCAAAAAGTG CTGGCCGACT ACGAAAATTC AACGCTGCCT CGTCCACGCC CAACGCGTGG 7140
TCCGCCGCTA CACCACCACC AACCCACGCA CCGATGCCGG GCGCACCATC TACCGACTTG 7200
CGCTGAAACT GACCCGGATC ACCACACTGG ATGAAGCCGC CGCGTGGGGT GTGCAACTGC 7260
ACGAGTTTTC AACGATCTAC CGGGAATGGA TGAACGAGAA AACCATGATC AAAGACCCCA 7320
AAACAGGTGC ATGGACCCGC GTGTGGACCC ACCACAACGT GCGCAAGGCC TACAACAGCC 7380
TCAACCATCT TTGGCGGTCC GAGATGCTGT TTGTCTACCT CAACCCGCCA GCAGGAGTCC 7440
TTGCGCCCGA GCGGATCAAA TCCACCACCA ACAGCTTAGA AGGCGGCATC AACGCCCAGC 7500
TCAAACTGCT CGCCAGAACC CACCGCGGCA GATCAGGCGA ACGACAACGC CGCATGCTGG 7560
ATTGGTGGCT CTACTTAAAA ACGGAACTGC CTGACGATCC AGTACGAATC GCCAGGCAGT 7620
CCGACTGGGG CCAGGGCCAA CTCGCCAAAG TATCCACCCT GACCCAAACC GAGAACCAAG 7680
CCGACCACGA AACAGGACGC CCAGCCCTCT ACGACAACGC TATCGACACC GACTACACCC 7740
ACTCAATCGG CATTCAAAAA GGCCAAATCT AACCCCCGCG ACACGCCGAG CCAGACACAC 7800
ATTTTGACCC TTAACCCACT TGCTTTGGAC ATAAAAAAGC TCCCAGGCAT CCCCGGGAGC 7860
TTGTCTCGGG CATCCCCGAG ACGTCGGAAT AACCGAAAGG AATCAGTTAA ACACTCGACA 7920
CGATTGATCG TAGAAAACGT AGCCGAAAAA AGCAACAAAC TCCCACGTGA GACGTAAAAT 7980
CAAAGCTCCC AATTAAACAT ATGCCAAGAC ATATGTTTAA GCATATGGCT TAACATATGG 8040
CAGAACATAT GCTAATATGA AACCCACAGC TCAAAGGATT TGAGAACACA ACACTCGACA 8100
CCTAAAAGGA GCAGCCATGC CCGTAATTTC CTGCCTCAAC GCCAAAGGCG GAACCGGAAA 8160
AACCACCAGC GCAATCAACC TCGCCGCCGT CGCCGCCTAC CGTGGATACA CCGTCCACGT 8220
CCTCGACGCC GACGCCGAAC AAGGCACCGC CTCCGAATGG ATCGAATACG CCAACGACGC 8280
CTTCGAAGAA AACCCCAACG CCCCCCACGT TGACGTCGAA GTCGAAGCCG TCAACCGAGG 8340
AATCCTCGCG CGCAAGGTAA AAAAATACAG CGACGACCTT GTCATCATCG ACGGCCCACC 8400
CAGCAATCAC AGCATGTCTG AACTCATCAT CGAAAACTCA GACTTCGTCG TCATTCCCAC 8460
CACCGGCACC CACACGGATA TGGCACAAAC CTGGAAAATC ATCGACGTCA TTCCAGAAGG 8520
CAAACACTAC GCCGTACTGC CCACCATCTG GGACAAGCGC AAAAGCACTG CCGACCGCGC 8580
CCGGAAAGTC CTTGAAGACG AAGGAATCCC AGTCATTTGG CCCGGCGTAG AATCCCGCGC 8640
CTACTTCGAC CGCCAATTCG GACACTGGCC CCGCAACAGC GCCAAAGAAC TACACGGCTA 8700
TCCCGCAATC TTTGACAAAA TCATCGCCCA AATCACCAAC TAACCACACC TTAAAAAGGA 8760
GCAACCATGA ACGACACCCC AGGACTGGCA CGCCCGAAAA AGAAGCAAAC CGACGCCCAA 8820
GGAAAACCCA CCCTCACCAA AGACACCGGA CTTAATACCA CCAAGGTCAC AAAGGCCACC 8880
AAGAAAGAAA AGCCCCACCG CACCACCGTC AACCTGCCCT ACTCCATCTA CAAAGAACTA 8940
CGCAGAAACT GGGCAGAAAC CAGCACCCCT ATCTACCGCC AACTTCTAGA 8990
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