Class D (Plasmid pRA1 - tetA gene)

ID   PPTETD     standard; DNA; PRO; 1279 BP.
XX
AC   L06798;
XX
NI   g309957
XX
DT   07-JAN-1993 (Rel. 34, Created)
DT   18-JUL-1995 (Rel. 44, Last updated, Version 2)
XX
DE   Plasmid pRA1 class D tetracycline/H+ antiporter (tetD) gene,
DE   complete cds.
XX
KW   antibiotic resistance; tetD gene; tetracycline resistance;
KW   tetracycline/H+ antiporter.
XX
OS   unidentified bacterium
OC   Eubacteria; environmental samples.
XX
OG   Plasmid pRA1
XX
RN   [1]
RP   1-1279
RX   MEDLINE; 93319254.
RA   Varela M.F., Griffith J.K.;
RT   "Nucleotide and deduced protein sequence of the class D
RT   tetracycline resistance determinant: Relationship to other
RT   antimicrobial transport proteins";
RL   Antimicrob. Agents Chemother. 37:1253-1258(1993).
XX
DR   SPTREMBL; Q52265; Q52265.
XX
CC   NCBI gi: 309957
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1279
FT                   /organism="Bacteria"
FT                   /plasmid="Plasmid pRA1"
FT                   /sequenced_mol="DNA"
FT   CDS             47..1231
FT                   /gene="tetD"
FT                   /standard_name="TetD"
FT                   /note="putative; NCBI gi: 309958"
FT                   /codon_start=1
FT                   /function="tetracycline resistance"
FT                   /product="class D tetracycline/H+ antiporter"
FT                   /db_xref="PID:g309958"
FT                   /db_xref="SPTREMBL:Q52265"
FT                   /translation="MNKPAVIALVITLLDAMGIGLIMPVLPSLLREYLPEADVANHYGI
FT                   LLALYAVMQVCFAPLLGRWSDKLGRRPVLLLSLAGAAFDYTLLALSNVLWMLYLGRIIS
FT                   GITGATGAVAASVVADSTAVSERTAWFGRLGAAFGAGLIAGPAIGGLAGDISPHLPFVI
FT                   AAILNACTFLMVFFIFKPAVQTEEKPAEQKQESAGISFITLLKPLALLLFVFFTAQLIG
FT                   QIPATVWVLFTESRFAWDSAAVGFSLAGLGAMHALFQAVVAGALAKRLSEKTIIFAGFI
FT                   ADATAFLLMSAITSGWMVYPVLILLAGGGIALPALQGIISAGASAANQGKLQGVLVSLT
FT                   NLTGVAGPLLFAFIFSQTQQSADGTVWLIGTALYGLLLAICLLIRKPAPVAATC"
XX
SQ   Sequence 1279 BP; 230 A; 324 C; 404 G; 321 T; 0 other;
     TATTCCAACT CTATCAATGA TAGGGAATTA ACACAGGATC TGAAAAATGA ATAAACCCGC        60
     TGTCATCGCG CTGGTGATTA CACTGCTGGA CGCGATGGGA ATTGGTCTGA TCATGCCGGT       120
     ATTACCGTCA CTGCTGCGGG AATATCTCCC GGAAGCGGAT GTGGCAAACC ATTACGGCAT       180
     TCTGCTGGCG CTGTATGCGG TGATGCAGGT CTGTTTTGCT CCGCTGCTGG GCAGATGGTC       240
     AGATAAGCTG GGGCGCAGAC CGGTGCTGCT GTTATCCCTG GCGGGTGCCG CGTTTGATTA       300
     CACACTGCTG GCACTGTCCA ATGTGCTGTG GATGTTGTAT CTCGGGCGGA TTATCTCCGG       360
     GATCACTGGT GCCACCGGCG CGGTTGCGGC TTCGGTAGTG GCGGACAGCA CGGCGGTCAG       420
     CGAGCGTACC GCCTGGTTCG GCCGTCTCGG TGCGGCCTTT GGTGCCGGGC TGATTGCCGG       480
     GCCGGCTATC GGCGGACTGG CGGGGGATAT CTCACCGCAT CTGCCGTTTG TCATTGCGGC       540
     AATACTGAAT GCCTGCACCT TTCTGATGGT CTTTTTTATC TTTAAACCGG CGGTACAGAC       600
     AGAAGAAAAA CCGGCGGAGC AGAAACAAGA AAGCGCAGGT ATCAGCTTTA TCACACTGCT       660
     TAAACCTCTG GCGCTGTTGC TGTTTGTCTT TTTTACCGCG CAGCTTATCG GGCAGATCCC       720
     GGCCACTGTC TGGGTATTGT TTACGGAGAG CCGCTTTGCC TGGGACAGCG CGGCGGTCGG       780
     TTTTTCACTG GCGGGACTCG GGGCGATGCA TGCACTGTTT CAGGCGGTGG TTGCCGGGGC       840
     GCTGGCAAAA CGGCTGAGTG AGAAAACCAT TATTTTCGCC GGATTTATTG CCGATGCCAC       900
     CGCGTTTTTA CTGATGTCTG CTATCACTTC CGGATGGATG GTGTATCCGG TCCTGATCCT       960
     GCTGGCAGGC GGCGGAATTG CACTGCCTGC ATTGCAGGGC ATTATCTCTG CCGGGGCATC      1020
     GGCGGCAAAT CAGGGAAAAC TACAGGGTGT GCTGGTCAGC CTGACCAATC TGACCGGCGT      1080
     GGCGGGCCCG CTGCTGTTTG CTTTTATTTT CAGTCAGACA CAGCAGAGTG CGGACGGTAC      1140
     GGTGTGGCTG ATTGGCACGG CACTGTACGG TCTGCTGCTG GCAATCTGTC TGCTGATCAG      1200
     AAAACCGGCA CCGGTGGCGG CCACCTGCTG ACCGGCGCTA TACAGGCAGC GCTGTTGTGC      1260
     GGTATGGTGG ACGGCATTC                                                   1279
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