Class O (Campylobacter coli - pIP1433 - TetO protein)

ID   TETO_CAMCO     STANDARD;      PRT;   639 AA.
AC   P23835;
DT   01-NOV-1991 (REL. 20, CREATED)
DT   01-NOV-1991 (REL. 20, LAST SEQUENCE UPDATE)
DT   01-OCT-1993 (REL. 27, LAST ANNOTATION UPDATE)
DE   TETRACYCLINE RESISTANCE PROTEIN TETO.
GN   TETO.
OS   CAMPYLOBACTER COLI.
OC   PROKARYOTA; GRACILICUTES; SCOTOBACTERIA;
OC   AEROBIC, MOTILE, HELICAL AND/OR VIBRIOID.
RN   [1]
RP   SEQUENCE FROM N.A.
RA   SOUGAKOFF W., PAPADOPOULOU B., NORDMANN P., COURVALIN P.;
RL   FEMS MICROBIOL. LETT. 44:153-159(1987).
CC   -!- FUNCTION: ABOLISH THE INHIBITORY EFFECT OF TETRACYCLIN ON PROTEIN
CC       SYNTHESIS BY A NON-COVALENT MODIFICATION OF THE RIBOSOMES
CC       (PROBABLE).
CC   -!- SIMILARITY: VERY HIGH TO OTHER TETM/TETO PROTEINS.
CC   -!- SIMILARITY: TO GTP-BINDING ELONGATION FACTORS.
DR   PIR; S06388; S06388.
DR   PROSITE; PS00301; EFACTOR_GTP.
KW   PROTEIN BIOSYNTHESIS; ANTIBIOTIC RESISTANCE; GTP-BINDING.
FT   NP_BIND      10     17       GTP (BY SIMILARITY).
FT   NP_BIND      74     78       GTP (BY SIMILARITY).
SQ   SEQUENCE   639 AA;  72373 MW;  7DF3EA89 CRC32;
     MKIINLGILA HVDAGKTTLT ESLLYTSGAI AEPGSVDKGT TRTDTINLER QRGITIQTAV
     TSFQWEDVKV NIIDTPGHMD FLAEVYRSLS VLDGAVLLVS AKDGIQAQTR ILFHALQIMK
     IPTIFFINKI DQEGIDLPMV YQEMKAKLSS EIIVKQKVGQ HPHINVTDND DMEQWDAVIM
     GNDELLEKYM SGKPFKMSEL EQEENRRFQN GTLFPVYHGS AKNNLGIRQL IEVIASKFYS
     STPEGQSELC GQVFKIEYSE KRRRFVYVRI YSGTLHLRDV IRISEKEKIK ITEMCVPTNG
     ELYSSDTACS GDIVILPNDV LQLNSILGNE ILLPQRKFIE NPLPMLQTTI AVKKSEQREI
     LLGALTEISD GDPLLKYYVD TTTHEIILSF LGNVQMEVIC AILEEKYHVE AEIKEPTVIY
     MERPLRKAEY TIHIEVPPNP FWASVGLSIE PLLLGSGVQY ESRVSLGYLN QSFQNAVMEG
     VLYGCEQGLY GWKVTDCKIC FEYGLYYSPV STPADFRLLS PIVLEQALKK AGTELLEPYL
     HFEIYAPQEY LSRAYHDAPR YCADIVSTQI KNDEVILKGE IPARCIQEYR NDLTNFTNGQ
     GVCLTELKGY QPAIGKFICQ PRRPNSRIDK VRHMFHKLA
//