Tetracycline resistance gene classification:
Class G
© Service of Biosafety & Biotechnology
- Author:
Jean-Marc Collard
Last revised:
| MECHANISM |
|
Efflux | 12-TMS (Transmembrane segments) |
| Ribosomal protection | |||
| Enzymatic | |||
| Unknown |
| MINOCYCLINE RESISTANCE |
YES |
|
NO |
| DISTRIBUTION | Pseudomonas, Salmonella, Vibrio |
| REPRESENTATIVES | pJA8122 (Ref. 1) | tetA (G) |
| GENETIC LOCATION | Plasmid | Integron |
| SOURCE | Vibrio anguillarum MZ8122 | Salmonella typhimurium DT104 |
| SEQUENCE ACCESS NB | S52437 (Ref. 2) | AF07155 (Ref. 4)) |
| REPRESENTATIVES | pPSTG1 | pPSTG2 |
| GENETIC LOCATION | Plasmid | Plasmid |
| SOURCE | Pseudomonas sp. | Pseudomonas sp. |
| SEQUENCE ACCESS NB | AF133139 (Unpublished) | AF133140 (Unpublished) |
| PROTEIN WEIGHT | 40.9 kDa (Calculated) (Ref. 2) |
| PROBES | |
| PCR PRIMERS | see reference 3 |
| REFERENCES | |
| 1 | Aoki, T., T. Satoh, and T. Kitao. 1987. New tetracycline resistance determinant on R plasmid from Vibrio anguillarum. Antimicrob. Agents Chemother. 31:1446-1449. |
| 2 | Zhao, J., and T. Aoki. 1992. Nucleotide sequence analysis of the Class-G tetracycline resistance determinant from Vibrio anguillarum. Microbiol. Immunol. 36:1051-1060. |
| 3 | Hansen, L. M., P. C. Blanchard, and D. C. Hirsh. 1996. Distribution of tet(H) among Pasteurella isolates from the United States and Canada. Antimicrob. Agents Chemother. 40:1558-1560. |
| 4 | Briggs, C. E., and P. M. Fratamico. 1999. Molecular characterization of an antibiotic resistance gene cluster of Salmonella typhimurium DT104. Agents Chemother. 43:846-849. |