Tetracycline resistance gene classification:
Class S
© Service of Biosafety & Biotechnology
- Author:
Jean-Marc Collard
Last revised:
| MECHANISM | Efflux | |
|
Ribosomal protection | |
| Enzymatic | ||
| Unknown |
| MINOCYCLINE RESISTANCE |
|
YES |
NO |
| DISTRIBUTION | Gram-positives: Lactococcus, Listeria , Enterococcus |
| REPRESENTATIVES | pIP811 (Ref. 1) | pK214 (Ref. 5) |
| GENETIC LOCATION | Plasmid | Plasmid |
| SOURCE | Listeria monocytogenes BM4210 | Lactococcus lactis |
| SEQUENCE ACCESS NB | L09756 (Ref. 2) | X92946 |
| PROTEIN WEIGHT | 72.9 kDa (Calculated) (Ref. 2) |
| PROBES | 900-bp EcoRI-BglII of pIP811 or pAT451 (Ref. 2, 3) |
| PCR PRIMERS |
| REFERENCES | |
| 1 | Poyart-Salmeron, C., C. Carlier, P. Trieu-Cuot, A.-L. Courtieu, and P. Courvalin. 1990. Transferable plasmid-mediated antibiotic resistance in Listeria monocytogenes. The Lancet 335:1422-1426. |
| 2 | Charpentier, E., G. Gerbaud, and P. Courvalin. 1993. Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210. Gene 131:27-34. |
| 3 | Charpentier, E., G. Gerbaud, and P. Courvalin. 1994. Presence of the Listeria tetracycline resistance gene tet(S) in Enterococcus faecalis. Antimicrob. Agents Chemother. 38:2330-2335. |
| 4 | Francois, B., M. Charles, and P. Courvalin. 1997. Conjugative
transfer of tet(S) between strains of Enterococcus faecalis is associated
with the exchange of large fragments of chromosomal DNA. Microbiology 143:2145-2154. |
| 5 | Perreten, V., F. Schwarz, M. Boeglin, L. Cresta, G. Dasen, and M. Teuber. 1998. Antibiotic resistance spread in food. Nature 391:801-802. |