Tetracycline resistance gene classification:
Class U
© Service of Biosafety & Biotechnology
- Author:
Jean-Marc Collard
Last revised:
| MECHANISM | Efflux | |
|
Ribosomal protection (based upon minocycline resistance and some limited conserved sequences (21% over 105 AA) between the putative resistance determinant of pKQ10 and of tet(M), tet(O), and other ribosomal protection determinants: Ref. 1) | |
| Enzymatic | ||
| Unknown |
| MINOCYCLINE RESISTANCE |
(Ref . 1) |
YES |
NO |
| DISTRIBUTION | Enterococcus |
| REPRESENTATIVES | tet(U) |
| GENETIC LOCATION | Plasmid pKQ10 |
| SOURCE | Enterococcus faecium |
| SEQUENCE ACCESS NB | U01917 (Ref. 1) |
| PROTEIN WEIGHT | 11.8 kDa (Calculated) (Ref. 1) |
| PROBES | |
| PCR PRIMERS |
| REFERENCE | |
| 1 | Ridenhour, M. B., H. M. Fletcher, J. E. Mortensen, and L. Daneo-Moore. 1996. A novel tetracycline-resistance determinant, tet(U), is encoded on the plasmid pKQ10 in Enterococcus faecium. Plasmid 35:71-80. |