Tetracycline determinants: Class X

Tetracycline resistance gene classification: Class X

© Service of Biosafety & Biotechnology - Author: Jean-Marc Collard
Last revised: March 3, 1998

MECHANISM		Efflux
		Ribosomal protection
		Enzymatic
		Unknown

MINOCYCLINE RESISTANCE

YES

DISTRIBUTION

Bacteroides

REPRESENTATIVES	tetX
GENETIC LOCATION	Conjugative transposon Tn4351
SOURCE	Bacteroides
SEQUENCE ACCESS NB	M37699 (Ref. 1)

PROTEIN WEIGHT	43.7 kDa (Calculated) (Ref. 1)
PROBES
PCR PRIMERS

REFERENCES

1 Speer, B. S., L. Bedzyk, and A. A. Salyers. 1991. Evidence that a novel tetracycline resistance gene found on two bacteroides transposons encodes an NADP-requiring oxidoreductase. J. Bacteriol. 173:176-183.

2 Park, B.H., and S.B. Levy. 1988. The cryptic tetracycline resistance determinant on Tn4400 mediates tetracycline degradation as well as tetracycline efflux. Antimicrob. Agents Chemother. 32:1797-1800.

	REFERENCES
1	Speer, B. S., L. Bedzyk, and A. A. Salyers. 1991. Evidence that a novel tetracycline resistance gene found on two bacteroides transposons encodes an NADP-requiring oxidoreductase. J. Bacteriol. 173:176-183.
2	Park, B.H., and S.B. Levy. 1988. The cryptic tetracycline resistance determinant on Tn4400 mediates tetracycline degradation as well as tetracycline efflux. Antimicrob. Agents Chemother. 32:1797-1800.