Tetracycline resistance gene classification: otrC

© Service of Biosafety & Biotechnology - Author: Jean-Marc Collard
Last revised: March 3, 1998



MECHANISM Efflux
  Ribosomal protection
    Enzymatic
  Unknown

MINOCYCLINE RESISTANCE

YES

NO



DISTRIBUTION Gram-positives: Streptomyces


REPRESENTATIVES otrC
GENETIC LOCATION Chromosome
SOURCE Streptomyces
SEQUENCE ACCESS NB Unsequenced


PROTEIN WEIGHT
PROBES
PCR PRIMERS

  REFERENCES
1 Pang, Y., B.A. Brown, V.A. Steingrube, R.J. Wallace, and M.C. Roberts. 1994. Tetracycline resistance determinants in Mycobacterium and Streptomyces species. Antimicrob. Agents Chemother. 38:1408-1412.
2 Roberts, M. C. 1996. Tetracycline resistance determinants: mechanisms of action, regulation of expression, genetic mobility, and distribution. FEMS Microbiol. Rev. 19:1-24.