Tetracycline determinants: OtrB

Tetracycline resistance gene classification: tet
© Service of Biosafety & Biotechnology - Author: Jean-Marc Collard
Last revised: June 29, 1999

MECHANISM		Efflux
		Ribosomal protection
		Enzymatic
		Unknown

MINOCYCLINE RESISTANCE

YES

DISTRIBUTION

Streptomyces

REPRESENTATIVES	tet
GENETIC LOCATION	Chromosome
SOURCE	Streptomyces lividans
SEQUENCE ACCESS NB	M74049

PROTEIN WEIGHT
PROBES
PCR PRIMERS

REFERENCE

1 Dittrich, W., and H. Schrempf. 1992. The unstable tetracycline resistance gene of Streptomyces lividans 1326 encodes a putative protein with similarities to translational elongation factors and Tet(M) and Tet (O) proteins. Antimicrob. Agents Chemother. 36:1119-1124.

	REFERENCE
1	Dittrich, W., and H. Schrempf. 1992. The unstable tetracycline resistance gene of Streptomyces lividans 1326 encodes a putative protein with similarities to translational elongation factors and Tet(M) and Tet (O) proteins. Antimicrob. Agents Chemother. 36:1119-1124.